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Besides acting as an intermediate in an active DNA demethylation pathway, 5hmC may also serve as a stable neuronal epigenetic mark in its own right [43]
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If not converted to the corresponding alcohol (PLOH) by GPX4, PLOOH and lipid free radicalsin particular, PLOO and alkoxyl phospholipid radicals (PLO)will react with PUFA-PLs to propagate PLOOH production by removing more hydrogen atoms and reacting with molecular oxygen
