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Step four short term and long term schedule The exact schedule is tailored to you, but many adults follow a pattern similar to this, based on research and Spravato dosing guides (spravatohcp.com) Weeks one through four Usually two treatments each week This is called the induction phase and is meant to jump start relief Week five and beyond Treatments often change to once a week, then sometimes every other week The goal is to keep symptoms under control with the lowest helpful frequency Your provider checks your mood, side effects, and overall function at each visit

The key question will be long-term durability, safety, tolerability, and how these therapies perform in broader real-world populations beyond controlled trials

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