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Its fine for immediate, one-shot dilutions but unsuitable for ongoing research protocols

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This rapid increase in blood levels is particularly helpful for individuals with severe deficiency symptoms or those who require immediate intervention for medical conditions related to vitamin B12 deficiency

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There are tolerability concerns that can prevent patients from staying on medications

To ensure the regulated clearing of dead cells, it was suggested that dead cells express eat-me signals and lose dont-eat-me signals on their surface [213]