According to the National Academies of Sciences, Engineering, and Medicine (NAP), a safe highest level is called the tolerable upper intake level. Assessment of what amount is too much is based on animal and human studies, published evidence of adverse events, and professional agreement based on a committee of experts
It is important to keep redox balances of the cells, cell cycle regulation, apoptosis, immunological defense, and pathological abnormalities (1, 2)
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Any specific decimal-precision number cited without a human PK study should be treated as speculative
Sartorius et al., 2021
For the recommended 3mL reconstitution, draw exactly 3mL