A randomised clinical trial of monthly depot buprenorphine for treatment of opioid use disorder
Recent studies have identified a role for bone marrow precursors in the trafficking of immune cells to the gut, enabling development of intestinal intraepithelial lymphocytes (IELs) within the gut that express the GLP-1R (52)
Studies using FDA adverse event data found elevated reporting odds ratios for alopecia with semaglutide at 2.46 and tirzepatide at 1.73
Pharmacologically, Melanotan II is not tanning-only. It interacts with multiple melanocortin receptor subtypes, including those in the brain and peripheral tissues, which is why it can also affect appetite, sexual function, and blood pressure
Online pharmacies are expected to post the fastest channel growth at 5.05% CAGR through 2031, while retail pharmacies still held the largest channel share in 2025
Overall, the results of the PIONEER-3 study together with other recent studies suggest that the introduction of semaglutide , the first oral compound of GLP-1RA in which the subcutaneous agent has shown a positive cardiovascular benefit, is an important addition to the growing list of pharmacological options for the treatment of type-2 diabetes
