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Cagrilintide monotherapy remains investigational, and the CagriSema combination although it has been submitted for regulatory review remained unapproved as of this writing
Importantly, animals were singly housed to eliminate the exchange and cross-contamination of intestinal microbiomes, a factor that potentially biases studies with group-housed animals by minimizing microbiome variations for co-housed animals within a cohort
The discoloration itself isn't dangerous
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