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Higher KCC2 expression ensures a low [Cl ] i concentration such that GABA binding elicits Cl influx and cell hyperpolarization, potentiating inhibitory GABAergic signaling
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doi:10.1016/j.molmet.2017.11.009 Bozkaya G, Ozgu E, Karaca B
Its possible that one of the ways cinnamon is good for blood sugar is because it increases GLP-1
This creates a unique metabolic dance that the body needs time to adjust to, which is why the retatrutide dose schedule uses a gradual titration over many weeks
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