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You must exercise extreme caution, as many all-in-one cold remedies already contain acetaminophen or NSAIDs

Obviously, stability limits prevent that

Acetaldehyde, a byproduct of alcohol, disrupts the conversion of homocysteine to methionine, lowering cysteine and glutathione production and increasing homocysteine levels

Arendt et al., 2013)

Therefore, as evidenced by our results, different types of anticoagulants may differentially stabilize and prevent spontaneous oxidation of free GSH in plasma (with suggestive evidence that EDTA better prevents spontaneous oxidation than heparin)