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B-Complex $25 Contains Vitamins B1 (thiamine), B2 (riboflavin), B3 (niacinamide), B5 (dexpanthenol), B6 (pyridoxine hydrochloride) B vitamins are necessary for the proper functioning of the methylation cycle, DNA synthesis, repair and maintenance of phospholipids, and are generally essential for healthy skin, muscles, brain, and nerve functionality
Finally, a four-year, multicenter, clinical trial in 421 diabetic patients with distal symmetric sensorimotor polyneuropathy found no difference between oral administration of 600 mg/day of lipoic and placebo on the primary endpoint, a composite score that assessed neuropathic impairment of the lower limbs and nerve conduction (78)
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however, the evidence for efficacy on NAD + or health benefits is still largely lacking, raising the need to properly assess different delivery methodologies
