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In each individual case, we find one or more causes that contribute to hyperpigmentation in the area
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IL-10 is required for polarization of macrophages to M2-like phenotype by mycobacterial DnaK (heat shock protein 70)
This upregulation extends to key antioxidant systems, including glutathione (GSH) and thioredoxin (TRX), which help maintain redox balance and support tumor survival [35]
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