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A randomized controlled trial on the effect of metformin in CHD patients without diabetes showed that it (2000 mg/day, P.O for 12 months) not only decreased oxidative stress but also lowered left ventricular mass (LVM) and improved blood pressure [227]
A recent study further identified that diabetic rats treated with PLP experienced a reduction in problems associated with diabetes, including a decline in oxidative stress parameters, reductions in blood glucose levels, and damage recovery in the liver and kidneys (Abdullah 2019)
It is constantly being produced, used and then replenished
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Glutathione is a fragile molecule that is easily broken down by stomach acid and normal digestive processes
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