This method is particularly useful for peptides that target cognitive or neurological functions, as the nasal cavity provides a pathway that is close to the central nervous system
Scand J Haematol 1982;29:311-318 Pezacka E, Green R, Jacobsen DW
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10.1210/EN.2015-1110 Endocrinology 78 HwangI.ParkY
Neuroimaging studies have found that patients with hyperthyroidism had reduced grey matter volume in portions of the occipital lobe (lateral occipital sulcus and fusiform gyrus) in the left hemisphere, the frontal and parietal lobes (insula, paracentral, precuneus, superior frontal cingulate, superior parietal and postcentral) in the right hemisphere
10.3389/fimmu.2018.00754 Front Immunol