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Gross PM, Sposito NM, Pettersen SE, Fenstermacher JD

The trial randomized 263 participants across the U.S

If your weight loss begins to slow down or comes to a standstill while taking semaglutide, reaching out to your healthcare provider is key

These may include: Beta-blockers (propranolol) Antidepressants (amitriptyline, venlafaxine) CGRP inhibitors (erenumab, fremanezumab) Botox injections for chronic migraine prevention (15+ headache days per month) Neuromodulation Devices: As a non-medication treatment option, neuromodulation devices (like Nerivio, Cefaly, or gammaCore) use gentle electrical or magnetic stimulation to calm overactive pain pathways effective for both acute migraine relief and long-term prevention

On the other hand, a triplet combination that added garetosmab showed even better results - preserving more muscle and burning more fat

LY: Conceptualization, Methodology, Supervision, Writingoriginal draft, Writingreview and editing