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4 After 35, your methylation efficiency tends to decline alongside other age-related metabolic shifts, which is part of the reason some practitioners may suggest you choose methylated folate (5-methyltetrahydrofolate, or 5-MTHF) over standard folic acid

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The review identifies advantages such as high specificity and potency, alongside challenges including stability concerns and delivery limitations

doi: 10.1016/S0140-6736(20)30628-0 191 MeisterA.AndersonM

Do not exceed recommended dose