That changed in 2025 with the publication of SURMOUNT-5, the first randomized head-to-head trial, published in the New England Journal of Medicine
Understanding how these medications affect body composition may help explain why some patients experience new back or neck discomfort during major weight loss
Healthcare providers must remain vigilant and closely monitor this potentially life-threatening adverse event
Rotate injection sites with each dose to prevent tissue changes that can affect absorption
Matthews JE, Stewart MW, De Boever EH, Dobbins RL, Hodge RJ, Walker SE, et al
Tumor progression and metastatic potential IGF-1 LR3 can promote tumor cell invasion and metastasis by upregulating the expression of matrix metalloproteinases (MMP-2/9)