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The following individual and combined search terms were used: GLP-1, Semaglutide and Liraglutide, molecular mechanism, lipid metabolism, insulin metabolism, glucose homeostasis, energy expenditure obesity treatment, type 2 diabetes mellitus, side effects, clinical trials, treatment option, fatty liver disease, hypertension, neurodegenerative diseases, cardiovascular diseases, therapeutic options. Only articles published in the last 10 years are included, although older pivotal studies were added
Diabetes 63 , 37113720 (2014)
Longitudinal studies with DEXA scans and serum marker monitoring will be crucial to confirm these associations and elucidate underlying mechanisms.
In some of the large-scale clinical studies evaluating the safety of GLP-1RAs against CV disease, the effect on kidneys was evaluated as a secondary endpoint
They also provide an opportunity to discuss any challenges you face and receive additional support for your weight loss journey
Pulmonary Aspiration Because food stays in the stomach longer, there is a small risk of pulmonary aspiration
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