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Phase 2 trial data (Jastreboff et al., NEJM, 2023) showed mean body weight reductions of approximately 24% at 48 weeks with the highest dose, with no clear plateau observed
Some Reddit users express worry and even panic about the possible effects of the medication on their early pregnancy
SPL UNCLASSIFIED SECTION Contraception Use of ZEPBOUND may reduce the efficacy of oral hormonal contraceptives
It was noted that heart failure remained a complication with limited risk-based prevention in clinical practice [79]
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Profound Changes in Food Noise & Cravings Once youve been cruising on tirzepatide for several months, you might not even notice that food noise, or the spontaneous compulsions to eat, have partially or completely dissolved
