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Tirzepatide is administered as a once-weekly subcutaneous injection, with dosing typically initiated at 2.5 mg and increased by 2.5 mg every 4 weeks up to a maintenance dose of 5-15 mg based on tolerability and therapeutic response

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Predicted weight-loss trajectories after the study end points suggests ongoing weight loss with continued therapy

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With rapid industrialization in recent decades, heavy metal contamination in agricultural soils has significantly increased, posing serious threats to crop production and food safety