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50 M Morin significantly upregulated the expression of MITF, as well as its downstream TRP-1 and Trp-2 to increase melanin production in B16F10 mouse melanoma cells, and the mechanisms include the activation of ERK and p38 signaling pathways via the phosphorylated MAPK pathway (Shin et al., 2021)

Overall agreement 50%: A+ 15%, A 35%, A 20%, D 20%, D 5%, D+ 5%

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