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COX-2, cyclo-oxygenase-2

Renal function must be assessed before initiating metformin and monitored regularly

b , Pharmacological characterization of GLP-1R wild-type and StaR

This has implications for how to design human albumin-fused biologics, as QMP engineering may ensure a long plasma half-life, increased target exposure, and enhanced efficacy, despite potential C-terminal cleavage post-administration

Attaching a 16-carbon side chain (palmitic acid) to the peptide allowed the molecule to bind to the abundant blood protein albumin and keep it in circulation