Her journey in medicine began at the University of Alberta Faculty of Medicine and Dentistry, where she earned her Medical Degree, following which she completed a Pediatric Specialty Training at the University of Alberta
2 People who have DKD have increased rates of morbidity and mortality, mainly because of the high risk of cardiovascular (CV) events
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doi: 10.1016/j.bbrc.2023.05.094 30 MllerTDFinanBBloomSRD'AlessioDDruckerDJFlattPRet al
SGLT2 Inhibitors The EMPA-REG OUTCOME and CANVAS studies have shown favourable all-cause mortality and cardiovascular outcomes.11,12 Meta-analyses of CVOTs confirmed the cardiovascular benefits.17,18 Three studies from landmark CVOTs further stratified patients according to baseline characteristics.21,22,23 The benefits of SGLT2 inhibitors were more apparent in patients with a history of HF and reduced ejection fraction.22,23 However, baseline risk was higher in this group of patients, possibly accounting for higher absolute risk reductions in cardiovascular outcomes
10.1016/j.cmet.2012.06.015 37 GrillH