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10.1073/pnas.0408624102 Proc

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Digestive side effects such as nausea, constipation and bloating often begin improving as the medication leaves your system, though the timeline varies by drug and by person

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The SCN may synchronize the growth hormone (GH) secretion rhythm with the dimming cycle through somatostatin neurons, and the change of the clock system may be related to the pulsatile release of GH