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I think it's, you know, within the last six months, I believe if it's over six months, they can have it

however, this appears to be a dose-dependent effect

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Collagen peptides: the oral supplement with clinical evidence Among all the peptides discussed in this guide, collagen peptides have the strongest human clinical trial evidence for directly improving bone mineral density

10.1146/annurev-biochem-061516-045037 148 TakanoT

Sordo L, Du A, Sandadi V et al (2025) Leptin levels are associated with body mass index and Alzheimers disease in Down syndrome