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January 7, 2026
Compared with the metformin plus sulfonylurea combination, the lowest risk for all three investigated endpoints, namely MACE, severe hypoglycemia, and all cause-mortality, was seen for people treated with metformin in combination with SGLT2is and GLP-1RAs (HR, 0.53 [95% CI, 0.350.80] for MACE
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Participants who took longer to reach the full dose achieved similar total weight loss to those who followed the standard schedule
The effects of L-carnitine for weight loss may differ from person to person
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