Marchi KC, Ceron CS, Muniz JJ, De Martinis BS, Tanus-Santos JE, Tirapelli CR
however, the nanoemulsion formulation demonstrated superior efficacy in preventing motor impairments and mitochondrial dysfunction relative to free CUR (111)
It is recognized for its stability and high resistance to enzymatic degradation, making it a valuable compound for controlled laboratory investigation
For patients seeking weight loss who request B12 injections, GPs should: Assess for genuine deficiency through appropriate blood tests rather than empirical treatment Provide education about the lack of evidence supporting B12 for weight loss in non-deficient individuals Explore underlying concerns about weight and energy levels, addressing these through appropriate channels Signpost to evidence-based resources such as NHS weight management services according to local pathways Patients should contact their GP if they experience unexplained fatigue, neurological symptoms (numbness, tingling, balance problems), or signs of anaemia (pallor, breathlessness, palpitations), as these may indicate B12 deficiency requiring investigation
Do not flush them down the toilet or throw them in household waste
M.CrowleyJ