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11 When to seek professional help If you notice the following, it's time to check in with a health care provider: 12 Twitching lasts more than two to three weeks without relief or a clear cause The twitching is focal and repetitive in one specific area You notice accompanying symptoms, such as muscle weakness, atrophy (shrinking), cramping, slurred speech, or poor coordination You suspect it's medication-related or linked to recent illness There's a family history of neurological conditions Possible interventions If needed, your health care provider may refer you for EMG, nerve conduction studies, or MRI to rule out underlying neurological or metabolic causes