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[1] [3] A family of histone deacetylases known as sirtuins (Sirt 1-7) controls a number of proteins involved in cellular metabolism, stress responses, circadian rhythms, and endocrine functions

After a single intravenous (IV) administration, single intramuscular (IM) administrations at three doses in successive increments along with repeated IM administrations, the elimination half-life (t 1/2 ) of prototype BPC157 was less than 30 min, and BPC157 showed linear pharmacokinetic characteristics in rats and beagle dogs at all doses

All current evidence is animal or in vitro no completed human trials exist for Dihexa itself

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Effect of peptide preparation epithalamin on circadian rhythm of epiphyseal melatonin-producing function in elderly people