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Discontinuing the medication often leads to regaining some of the lost weight

Bock-Marquette, I., et al

The report was uncontrolled, unblinded, not randomized, had no comparator arm, used patient-reported outcomes rather than validated pain instruments, and did not publish dose, effect size, confidence intervals, p-values, or systematically collected adverse events limitations that severely constrain any clinical inference

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9 Scientific American reports that during weight loss, the body does not exclusively use fat tissue