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The FDA approved Zepbound on November 8, 2023 for chronic weight management, that is, for obesity (BMI of 30 or above) or excess weight (BMI of 27 or above) with at least one weight-related comorbidity
Allow me to explain: Recent research has shown that GLP-1s affect digestion by slowing gastric emptying (the time it takes for food to leave your stomach) (1)
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China Patent CN102559529 (B) Wang Y, Wang D, Wei G, Wang C (2013b) Improved co-production of S-adenosylmethionine and glutathione using citrate as an auxiliary energy substrate
OTC patches have zero controlled data
Some symptoms include: fatigue, trouble losing weight, brain fog, blood sugar imbalances, trouble building muscle, muscle wasting, intestinal permeability, and hair loss
GLP-1R agonism not only helps with weight management but also appears to provide neuroprotective effects, including reducing neuroinflammation and enhancing brain health
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