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TMAO induces pyroptosis of tumor cells by activating the endoplasmic reticulum stress kinase PERK, thus enhancing the antitumor immune effect of CD8+ T cells
The receptors of other peptide agonists may be present at the hepatocyte, e.g., GCG receptor, through which cotadutide was supported to have direct hepatic effects [45]
+ What is preserved saline (Bacteriostatic Sodium Chloride) used for
Furthermore, ROS-induced oxidative inactivation of PTP1B phosphatase at the Cys215 site exacerbates insulin signaling transduction impairment [344]
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