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Semaglutide : STEP 1 demonstrated 14.9% mean weight loss at 2.4 mg over 68 weeks

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Viral-like TLR3 induction of cytokine networks and -synuclein are reduced by complement C3 blockade in mouse brain

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In a direct head-to-head trial (REDEFINE-4), tirzepatide edged CagriSema 25.5% to 23.0% at 84 weeks

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