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Some benefits, such as improved skin tone and enhanced immunity, develop progressively with regular sessions

Lancet 2018;391:54151

One notable difference: semaglutide and tirzepatide have established prescribing information with FDA-approved dose ranges and flexibility for clinicians to hold patients at intermediate doses if tolerability is an issue

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[14] Jastreboff AM, et al

Some providers specifically recommend microdosing for this population to allow metabolic adjustment without exacerbating hormonal symptoms