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In summary, the relatively higher expression of GLP-1R on -cells allows GLP-1 to indirectly inhibit glucagon secretion by promoting somatostatin secretion
Its proven anti-inflammatory effect (particularly in respect to heart health), the role of the reninangiotensin system in heart health and the immune response in general, and the importance of inflammation in infection led Lonza to explore the impact of L-carnitine on COVID-19 outcomes
Two randomized controlled trials demonstrated reduced bone loss during weight loss with GLP-1 RA compared to placebo (51, 52)
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