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Some patients report mild diarrhoea, nausea, or headache following administration, though these symptoms are usually transient
Shils, J
The frequency of vitamin injections depends on the patients health needs, how quickly their system uses up the nutrients, and what they hope to achieve with treatment
Groups at increased risk of B12 deficiency include: Vegans and strict vegetarians , who avoid all animal products and are at significant risk without supplementation or fortified foods Older adults , in whom reduced stomach acid production impairs B12 absorption People with pernicious anaemia , an autoimmune condition that destroys intrinsic factor-producing cells Those who have undergone gastric surgery , including bariatric procedures, which can reduce intrinsic factor availability Individuals taking long-term metformin for type 2 diabetes, as this medication is associated with reduced B12 absorption the MHRA has issued specific safety advice on monitoring B12 levels in this group [6] [7] People with conditions affecting the small intestine , such as Crohn's disease or coeliac disease Symptoms of B12 deficiency can include fatigue, weakness, pins and needles, memory difficulties, and a sore or inflamed tongue (glossitis)
For multi-dose vials used over weeks, bacteriostatic water is the standard because the benzyl alcohol preservative allows safe repeated draws without bacterial contamination risk
If you are unsure how to proceed you can always take a series of 10 shots and then monitor your symptoms after you are done to see if they get worse on weeks 11-13
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