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Reactions can result from: Repeated injections in the same area Improper injection technique (too shallow or too deep) Cold medication directly from the fridge Allergic sensitivity to the drug or preservative Injecting medication thats too cold can irritate tissue and cause pain or redness
The net impact on blood sugar when both are used together is unpredictable without clinical data
Both tirzepatide and semaglutide are FDA-approved, have support from more long-term data, and are already used in real-life settings
doi: 10.1111/dom.12398 27 FarngrenJPerssonMAhrenB
14.4 MOUNJARO Use in Combination with Basal Insulin with or without Metformin in Adult Patients with Type 2 Diabetes Mellitus SURPASS-5 (NCT04039503) was a 40-week double-blind trial that randomized 475 adult patients with type 2 diabetes mellitus with inadequate glycemic control on insulin glargine 100 units/mL, with or without metformin, to subcutaneous MOUNJARO 5 mg, MOUNJARO 10 mg, MOUNJARO 15 mg once weekly, or placebo
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