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c , Protein levels from cancer cell lines from DepMaps CCLE (Proteomics GGT1: P19440 (n = 339), GGT5: P36269 (n = 108), GGT6: Q6P531 (n = 45), GGT7: Q9UJ14 (n = 375))

Recent research has shown that silymarin reduces acute toxic liver injury caused by APAP by increasing hepatocyte proliferation, decreasing CYP2E1 activity and expression, and decreasing the production of toxic metabolites (Yang et al., 2022b)

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Int J Biochem Cell Biol 2006

Thus, glutamine metabolism not only sustains tumor bioenergetics and biosynthesis but also shapes an immunosuppressive niche that facilitates cancer progression (107)

Wise J (2023)