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These findings have particular relevance for ankle sprains, where ligament integrity determines long-term stability

61 The primary targets of the released zinc are NMDARs containing GluN2A, which are responsive to nanomolar levels of extracellular zinc, thereby inhibiting receptor function

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While not contaminated or unsafe, aggregated peptide exhibits significantly reduced bioavailability (typically 4065% lower) because aggregates cannot cross cell membranes efficiently

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