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MC3 (Melanocortin 3) Receptor Agonism Regulates sexual behavior (CNS): MC3 activation in the hypothalamus and other brain regions modulates appetite and mediates aspects of sexual arousal and proceptive sexual behavior, such as solicitation and increased sexual motivation in animals 1-3

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Before we dive into the background science, here is an essential regulatory update

Do DPP-4 inhibitors cause heart failure events by promoting adrenergically mediated cardiotoxicity