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Never expose to high heat Avoid these conditions: Leaving pens in a hot car Direct sunlight Placing pens near heaters or radiators Heat can permanently damage the medication

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These sorts of ideas would help to ensure that large-scale access can be targeted to those who would most benefit (rather than those who are easiest to reach) whether in populous countries (where the largest health gains are to be found) or countries with extremely high rates of obesity like small island developing states (where the most transformative changes in disease prevalence could be achieved)