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The side effects may be reduced when patients begin therapy at low doses and increase to higher doses slowly over time. Patients should also be evaluated for misuse risks, adds Devnani, as some patients may become addicted to the drugs

Moreover, recent studies have explored the potential link between elevated TMAO levels and various cancers

In contrast, GLP-1RAs enhance incretin signaling, increasing glucose-dependent insulin secretion, suppressing glucagon, delaying gastric emptying, and promoting satiety [20]

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