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Mounjaro can be used as first-line pharmacotherapy

Preclinical data suggests this effect persists with chronic treatment

Exposure to sugars induces rapid GLP-1 secretion from T1R3-sensitive cells, following a dose-dependent pattern where higher stimulus concentrations lead to greater secretionan effect blocked by GLP-1 receptor antagonists (61, 67)

Using 10,000 IU heparin in 10cm 3 sterile water three times a week for three months with retention of one hour, at three months 56% of patients reported clinically significant improvement

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