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Extraction of intracellular metabolites, GC-MS measurement, MID calculations, determinations of fractional carbon contributions, and subtractions of natural isotope abundance were performed as described 44
More specifically speaking, the mechanism potentially involved downregulation of macrophage CD11b, which played a vital role in monocyte adhesion, as well as decreased expression of macrophage modulators including CXCL-10, CXCL-1, C-C motif chemokine ligand-1 (CCL-2) and tissue inhibitor of metal protease-1 (TIMP-1) (Robinson et al., 2015)
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