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Bull Exp Biol Med 2003;135:5902
this effect is not dependent on the activation of G-protein-coupled melatonin receptors but on nuclear factor-kappa B (NF-B) 77
Granted, its a small difference, but, hey, it didnt hurt
282,283 These cells accumulate in the synovial membrane and subchondral bone, releasing pro-inflammatory cytokines such as TNF-, IL-1, and IL-6, which promote the degradation of joint cartilage and the inflammatory response