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Significantly, it has been discovered that the CYSS/glutamate antiporter system operates independently of intracellular GSH redox status instead of responding to the availability of extracellular CYSS (71)
10.1016/j.repbio.2019.12.009 193 SklanE
In research models, this mechanism has been studied in the context of photoprotection in UV-sensitive conditions particularly erythropoietic protoporphyria (EPP), where clinical development of afamelanotide as a subcutaneous implant has resulted in regulatory approval in Europe and the United States
Your body needs vitamin C to help heal wounds, keep your bones and teeth strong, and to help absorb iron in your body
