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However, tirzepatide's glucose-dependent mechanism of action means that hypoglycemia risk is low when used as monotherapy or with metformin

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The nausea, bloating, or other digestive symptoms some people experience are temporary reactions to this slowed digestion not evidence of lasting harm

Its a dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1

Clete References Centers for Medicare & Medicaid Services