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The researchers documented significantly lower frontal gray matter glutathione levels compared to healthy controls, directly linking this localized, severe oxidative stress to the clinical presentation of brain fog and memory loss

Long-Term Effects of Excessive Doses Continuous use of large amounts of methylcobalamin over a period can lead to issues like kidney stress and nerve damage while causing imbalances in important vitamins and minerals in the body

The association between polymorphisms of GST genes and the risk of epilepsy has been investigated in several studies 60,61,62