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The tryptophan-kynurenine pathway functions as a stress-activated metabolic system that diverts tryptophan from serotonin synthesis toward kynurenic acid production, which acts as a glutamate receptor antagonist and may contribute to anxiety pathophysiology through altered glutamatergic neurotransmission (Butler et al., 2022)
These will lead to various symptoms of irritation such as itch, erythema, edema and pain
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However, their appetite-suppressing qualities have led to their off-label use and approval for weight loss
Contraindications include known allergy to any component of the injection formulation
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