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Overall tolerability of the treatment was good, with the most common side effect being nausea, particularly during treatment initiation or dose adjustments, while diarrhea was reported by 5% of patients, which was dose-dependent and easily managed

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Efficacy and Safety of Oral Semaglutide With Flexible Dose Adjustment Versus Sitagliptin in Type 2 Diabetes (PIONEER 7): A Multicentre, Open-Label, Randomised, Phase 3a Trial

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They'll also screen for contraindications specific to semaglutide, including personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2