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NICE recommends lifestyle modifications and PDE5 inhibitors such as sildenafil, tadalafil, vardenafil, and avanafil as first-line pharmacological treatments
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Angiogenic signaling is a recurring theme in this area because vascular development plays an essential role in delivering oxygen, nutrients, and osteogenic precursor cells to healing bone tissue
However, at subpathogenic doses, LPS may exert compensatory effects
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