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Weeks 24: Improved sleep quality (deeper sleep is a common early report)

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Minocycline is a tetracycline that was demonstrated to not only modulate the dopaminergic and glutamatergic CNS signaling but also to restore the physiologic Firmicutes/Bacteroidetes ratio in the gut with positive effect on hypertension (162)

Diabetes research and clinical practice , 157 , 107843

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